For a complete list of publications, please visit our Pubmed.

Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice
Journal of Biological Chemistry
February 2022
Dhaval P. Bhatt, C. Allie Mills, Kristin A. Anderson, Bárbara J. Henriques, Tânia G. Lucas, Sara Francisco, Juan Liu, Olga R. Ilkayeva, Alexander E. Adams, Shreyas R. Kulkarni, Donald S. Backos, Michael B. Major, Paul A. Grimsrud, Cláudio M. Gomes, Matthew D Hirschey

Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract
Nature Communications
January 2022
Jianan Zhang , Morgan E. Walker, Katherine Z. Sanidad, Hongna Zhang, Yanshan Liang, Ermin Zhao, Katherine Chacon-Vargas, Vladimir Yeliseyev, Julie Parsonnet, Thomas D. Haggerty, Guangqiang Wang, Joshua B. Simpson, Parth B. Jariwala , Violet V Beaty, Jun Yang, Haixia Yang, Anand Panigrahy, Lisa M Minter, Daeyoung Kim, John G Gibbons, LinShu Liu, Zhengze Li, Hang Xia, Valentina Borlandelli, Hermen S. Overkleeft, Erica W Cloer, Michael B. Major , Dennis Goldfarb, Zongwei Cai, Matthew R. Redinbo, Guodong Zhang

Visualizing an Allosteric Intermediate Using CuAAC Stabalization of an NMR Mixed Labeled Dimer
ACS Chemical Biology
December 2021
Paul J. Sapienza, Michelle M. Currie, Noah M. Lancaster, Kelin Li, Jeffrey Aubé, Dennis Goldfarb, Erica W. Cloer, Michael B. Major, Andrew L. Lee

Correlation of alterations in the KEAP1/CUL3/NFE2L2 pathway with radiation failure in larynx squamous cell carcinoma
Laryngoscope Investigative Otolaryngology
August 2021
Siddharth Sheth, Douglas R. Farquhar, Travis P. Schrank, Wesley Stepp, Angela Mazul, Michele Hayward, Nicholas Lenze, Paul Little, Heejoon Jo, Michael B. Major, Bhishamjit S. Chera, Jose P. Zevallos, D. Neil Hayes

Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell
Cell Reports
July 2021
Maritza Puray-Chavez, Kyle M. LaPak, Travis P. Schrank, Jennifer L. Elliott, Dhaval P. Bhatt, Megan J. Agajanian, Ria Jasuja, Dana Q. Lawson, Keanu Davis, Paul W. Rothlauf, Zhuoming Liu, Heejoon Jo, Nakyung Lee, Kasyap Tenneti, Jenna E. Eschbach, Christian Shema Mugisha, Emily M Cousins, Erica W. Cloer, Hung R. Vuong, Laura A. VanBlargan, Adam L. Bailey, Pavlo Gilchuk, James E. Crowe Jr, Michael S. Diamond, D. Neil Hayes, Sean P.J. Whelan, Amjad Horani, Steven L. Brody, Dennis Goldfarb, Michael B. Major, Sebla B. Kutluay

Genomic heterogeneity and copy number variant burden are associated with poor recurrence-free survival and 11q loss in human papillomavirus-positive squamous cell carcinoma of the oropharynx
Cancer
April 2021
Travis P. Schrank, Nicholas Lenze, Lee P. Landess, Alan Hoyle, Joel Parker, Asim Lal, Siddharth Sheth, Bhishamjit S. Chera, Samip N. Patel, Trevor G. Hackman, Michael B. Major, Natalia Issaeva, Wendell G. Yarbrough

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Autophagy
February 2021
Many authors including Michael B. Major

TRIM67 Regulates Exocytic Mode and Neuronal Morphogenesis via SNAP47
Cell Reports
February 2021
Fabio L. Urbina, Shalini Menon, Dennis Goldfarb, Reginald Edwards, Michael B. Major, Patrick Brennwald, and Stephanie L. Gupton

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Molecular Biology of the Cell
December 2020
Shalini Menon, Dennis Goldfarb, Tsungyo HO, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, Michael B. Major, and Stephanie L. Gupton

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
PLoS Biology
December 2020
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffery S. Damrauer, Feng Yan, Joseph S. Harrison, Michael B. Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, and Michael J. Emanuele