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Competitive kinase enrichment proteomics reveals that Abemaciclib inhibits GSK3β and activates WNT signaling

MCR
November 2017

Emily M. Cousins, Dennis Goldfarb, Feng Yan, Jose Roques, David B. Darr, Gary L. Johnson, and Michael B. Major

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Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability

PLoS One
April 2017

Jeran K. Stratford, Feng Yan, Rebecca A. Hill, Michael B. Major, Lee M. Graves, Channing J. Der, and Jen Jen Yeh

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Glycosylation of KEAP1 links nutrient sensing to redox stress signaling

EMBO
June 2017

Po‐Han Chen, Timothy J. Smith, Jianli Wu, Priscila F. Siesser, Brittany J. Bisnett, Farhan Khan, Maxwell Hogue, Erik Soderblom, Flora Tang, Jeffrey R. Marks, Michael B. Major, Benjamin M. Swarts, Michael Boyce, and Jen‐Tsan Chi

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The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome

Journal of Biological Chemistry
May 2017

Jason J. Yi, Smita R. Paranjape, Matthew P. Walker, Rajarshi Choudhury, Justin M. Wolter, Giulia Fragola, Michael J. Emanuele, Michael B. Major, and Mark J. Zylka