2017

Competitive kinase enrichment proteomics reveals that Abemaciclib inhibits GSK3β and activates WNT signaling
MCR
November 2017
Emily M. Cousins, Dennis Goldfarb, Feng Yan, Jose Roques, David B. Darr, Gary L. Johnson, and Michael B. Major

Genetic and pharmacological inhibition of TTK impairs pancreatic cancer cell line growth by inducing lethal chromosomal instability
PLoS One
April 2017
Jeran K. Stratford, Feng Yan, Rebecca A. Hill, Michael B. Major, Lee M. Graves, Channing J. Der, and Jen Jen Yeh

Glycosylation of KEAP1 links nutrient sensing to redox stress signaling
EMBO
June 2017
Po‐Han Chen, Timothy J. Smith, Jianli Wu, Priscila F. Siesser, Brittany J. Bisnett, Farhan Khan, Maxwell Hogue, Erik Soderblom, Flora Tang, Jeffrey R. Marks, Michael B. Major, Benjamin M. Swarts, Michael Boyce, and Jen‐Tsan Chi

The autism-linked UBE3A T485A mutant E3 ubiquitin ligase activates the Wnt/β-catenin pathway by inhibiting the proteasome
Journal of Biological Chemistry
May 2017
Jason J. Yi, Smita R. Paranjape, Matthew P. Walker, Rajarshi Choudhury, Justin M. Wolter, Giulia Fragola, Michael J. Emanuele, Michael B. Major, and Mark J. Zylka