2022
Deglutarylation of glutaryl-CoA dehydrogenase by deacylating enzyme SIRT5 promotes lysine oxidation in mice
Journal of Biological Chemistry
February 2022
Dhaval P. Bhatt, C. Allie Mills, Kristin A. Anderson, Bárbara J. Henriques, Tânia G. Lucas, Sara Francisco, Juan Liu, Olga R. Ilkayeva, Alexander E. Adams, Shreyas R. Kulkarni, Donald S. Backos, Michael B. Major, Paul A. Grimsrud, Cláudio M. Gomes, Matthew D Hirschey
Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract
Nature Communications
January 2022
Jianan Zhang , Morgan E. Walker, Katherine Z. Sanidad, Hongna Zhang, Yanshan Liang, Ermin Zhao, Katherine Chacon-Vargas, Vladimir Yeliseyev, Julie Parsonnet, Thomas D. Haggerty, Guangqiang Wang, Joshua B. Simpson, Parth B. Jariwala , Violet V Beaty, Jun Yang, Haixia Yang, Anand Panigrahy, Lisa M Minter, Daeyoung Kim, John G Gibbons, LinShu Liu, Zhengze Li, Hang Xia, Valentina Borlandelli, Hermen S. Overkleeft, Erica W Cloer, Michael B. Major , Dennis Goldfarb, Zongwei Cai, Matthew R. Redinbo, Guodong Zhang
Protein proximity networks and functional evaluation of the casein kinase 1 gamma family reveal unique roles for CK1γ3 in WNT signaling
Journal of Biological Chemistry
June 2022
STING Suppresses Mitochondrial VDAC2 to Govern RCC Growth Independent of Innate Immunity
Advanced Science
November 2022
Zhichuan Zhu, Xin Zhou, Hongwei Du, Erica W. Cloer, Jiaming Zhang, Liu Mei, Ying Wang, Xianming Tan, Austin J. Hepperla, Jeremy M. Simon, Jeanette Gowen Cook, Michael B. Major, Gianpietro Dotti, and Pengda Liu
TP53, CDKN2A/P16, and NFE2L2/NRF2 regulate the incidence of pure- and combined-small cell lung cancer in mice
Oncogene
May 2022
Samera H. Hamad, Stephanie A. Montgomery, Jeremy M. Simon, Brittany M. Bowman, Kyle B. Spainhower, Ryan M. Murphy, Erik S. Knudsen, Suzanne E. Fenton, Scott H. Randell, Jeremiah R. Holt, D. Neil Hayes, Agnieszka K. Witkiewicz, Trudy G. Oliver, Michael B. Major, and Bernard E. Weissman