2023

Hepatic palmitoyl-proteomes and acyl-protein thioesterase protein proximity networks link lipid modification and mitochondria
Cell Reports
November 2023
Speck SL, Bhatt DP, Zhang Q, Adak S, Yin L, Dong G, Feng C, Zhang W, Major MB, Wei X, and Semenkovich CF

KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle
Journal of Virology
March 2023
Danielle L. Chappell, Praneet K. Sandhu, Jason P. Wong, Aadra P. Bhatt, Xiaoxi Liu, Sara J. Buhrlage, Brenda R. S. Temple, Michael B. Major, and Blossom Damania

Proximity proteomic analysis of the NRF family reveals the Parkinson’s disease protein ZNF746/PARIS as a co-complexed repressor of NRF2
Science Signaling
December 2023
LaPak KM, Saeidi S, Bok I, Wamsley NT, Plutzer IB, Bhatt DP, Luo J, Ashrafi G, and Major MB

Small molecule screen identifies pyrimethamine as an inhibitor of NRF2-driven esophageal hyperplasia
Redox Biology
November 2023
Paiboonrungruang C, Xiong Z, Lamson D, Li Y, Bowman B, Chembo J, Huang C, Li J, Livingston EW, Frank JE, Chen V, Li Y, Weissman B, Yuan H, Williams KP*, M. Major MB*, and Chen X*

Targeted proteomic quantitation of NRF2 signaling and predictive biomarkers in HNSCC
Molecular & Cellular Proteomics
September 2023
Wamsley NT, Wilkerson EM, Guan L, LaPak KM, Schrank TP, Holmes BJ, Sprung RW, Gilmore PE, Gerndt SP, Jackson RS, Paniello RC, Pipkorn P, Puram SV, Rich JT, Townsend RR, Zevallos JP, Zolkind P, Le Q-T, Goldfarb D, and Major MB