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Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling

ACS Chem Biol
December 2019

Parth B. Jariwala, Samuel J. Pellock, Dennis Goldfarb, Erica W. Cloer, Marta Artola, Joshua B. Simpson, Aadra P. Bhatt, William G. Walton, Lee R. Roberts, Michael B. Major, Gideon J. Davies, Herman S. Overkleeft, and Matthew R. Redinbo

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NRF2 Activation in Cancer: From DNA to Protein

Cancer Research
February 2019

Erica W. Cloer, Dennis Goldfarb, Travis P. Schrank, Bernard E. Weissman, and Michael B. Major

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Positive Cooperativity in Substrate Binding by Human Thymidylate Synthase

Biophysical Journal
August 2019

Jeffery P. Bonin, Paul J. Sapienza, Emily Wilkerson, Dennis Goldfarb, Li Wang, Laura Herring, Xian Chen, Michael B. Major, and Andrew L. Lee

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The MyMOMA domain of MYO19 encodes for distinct Miro-dependent and Miro-independent mechanisms of interaction with mitochondrial membranes

Cytoskeleton
September 2019

Jennifer L. Bocanegra, Barbara M. Fujita, Natalie R. Melton, James M. Cowan, Elizabeth L. Schinski, Tigist Y. Tamir, Michael B. Major, and Omar A. Quintero

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The Whole-Genome Landscape of Burkitt Lymphoma Subtypes

Blood
November 2019

Razvan I. Panea, Cassandra L. Love, Jennifer R. Shingleton, Anupama Reddy, Jeffrey A. Bailey, Ann M. Moormann, Juliana A. Otieno, John Michael Ong’echa, Cliff I. Oduor, Kristin M. S. Schroeder, Nestory Masalu, Nelson J. Chao, Megan Agajanian, Michael B. Major, Yuri Fedoriw, Kristy L. Richards, Grzegorz Rymkiewicz, Rodney R. Miles, Bachir Alobeid, Govind Bhagat, Christopher R. Flowers, Sarah L. Ondrejka, Eric D. Hsi, William W. L. Choi, Rex K. H. Au-Yeung, Wolfgang Hartmann, Georg Lenz, Howard Meyerson, Yen-Yu Lin, Yuan Zhuang, Micah A. Luftig, Alexander Waldrop, Tushar Dave, Devang Thakkar, Harshit Sahay, Guojie Li, Brooke C. Palus, Vidya Seshadri, So Young Kim, Randy D. Gascoyne, Shawn Levy, Minerva Mukhopadyay, David B. Dunson, and Sandeep S. Dave

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WNT Activates the AAK1 Kinase to Promote Clathrin-Mediated Endocytosis of LRP6 and Establish a Negative Feedback Loop

Cell Reports
January 2019

Megan J. Agajanian, Matthew P. Walker, Alison D. Axtman, Roberta R. Ruela-de-Sousa, D. Stephen Serafin, Alex D. Rabinowitz, David M. Graham, Meagan B. Ryan, Tigist Tamir, Yuko Nakamichi, Melissa V. Gammons, James M. Bennett, Rafael M. Couñago, David H. Drewry, Jonathan M. Elkins, Carina Gileadi, Opher Gileadi, Paulo H. Godoi, Nirav Kapadia, Susanne Müller, André S. Santiago, Fiona J. Sorrell, Carrow I. Wells, Oleg Federov, Timothy M. Willson, William J. Zuercher, and Michael B. Major