2018
Approximating Isotope Distributions of Biomolecule Fragments
ACS Omega
September 2018
Dennis Goldfarb, Michael J. Lafferty, Laura E. Herring, Wei Wang, and Michael B. Major
Computer-Aided Design and Synthesis of 1-{4[(3,4-Dihydroxybenzylidene)amino]phenyl}-5-oxopyrrolidine-3-carboxylic Acid as an Nrf2 Enhancer
ChemPlusChem
February 2018
Shirin Kahremany, Ilana Babaev, Pinhas Hasin, Tigist Y. Tamir, Tali Ben-Zur, Guy Cohen, Zhengyu Jiang, Sagiv Weintraub, Daniel Offen, Shai Rahimipour, Michael B. Major, Hanoch Senderowitz, and Arie Gruzman
Hyperactivity of the transcription factor Nrf2 causes metabolic reprogramming in mouse esophagus
Journal of Biological Chemistry
November 2018
Junsheng Fu, Zhaohui Xiong, Caizhi Huang, Jing Li, Wenjun Yang, Yuning Han, Chorlada Paiboonrungruan, Michael B Major, Keneng Chen, Xiaozheng Kang, and Xiaoxin Luke Chen
P62-dependent phase separation of patient-derived KEAP1 mutations and NRF2
Molecular and Cellular Biology
August 2018
E.W. Cloer, P.F. Siesser, E.M. Cousins, D. Goldfarb, D.D. Mowrey, J.S. Harrison, S.J. Weir, N.V. Dokholyan, M.B. Major
Ponatinib shows potent antitumor activity in small cell carcinoma of the ovary hypercalcemic type (SCCOHT) through multi-kinase inhibition
Clinical Cancer Research
February 2018
Jessica D. Lang, William P.D. Hendricks, Krystal A. Orlando, Hongwei Yin, Jeffrey Kiefer, Pilar Ramos, Ritin Sharma, Patrick Pirrotte, Elizabeth A. Raupach, Chris Sereduk, Nanyun Tang, Winnie S. Liang, Megan Washington, Salvatore J. Facista, Victoria L. Zismann, Emily M. Cousins, Michael B. Major, Yemin Wang, Anthony N. Karnezis, Aleksandar Sekulic, Ralf Hass, Barbara C. Vanderhyden, Praveen Nair, Bernard E. Weissman, David G. Huntsman, and Jeffrey M. Trent
Targeted therapy of esophageal squamous cell carcinoma: the NRF2 signaling pathway as target
Annals of the NYAS
May 2018
Shaohua Ma, Chorlada Paiboonrungruan, Tiansheng Yan, Kevin P. Williams, Michael B. Major, and Xiaoxin Luke Chen
The Cancer/Testes (CT) Antigen HORMAD1 promotes Homologous Recombinational DNA Repair and Radioresistance in Lung adenocarcinoma cells
Scientific Reports
October 2018
Yanzhe Gao, Jordan Kardos, Yang Yang, Tigist Y. Tamir, Elizabeth Mutter-Rottmayer, Bernard Weissman, Michael B. Major, William Y. Kim, and Cyrus Vaziri