2020
A circle RNA regulatory axis promotes lung squamous via CDR1-mediated regulation of Golgi trafficking
Cancer Research
September 2020
Emily B. Harrison, Alessandro Porrello, Brittany M. Bowman, Adam R. Belanger, Gabriella Yacovone, Salma H. Azam, Ian A. Windham, Subrata K. Ghosh, Menglin Wang, Nick McKenzie, Trent A. Waugh, Amanda E.D. Van Swearingen, Stephanie M. Cohen, Devon G. Allen, Tyler J. Goodwin, Teresa Mascenik, James E. Bear, Sarah Cohen, Scott H. Randell, Pierre P. Massion, Michael B. Major, Leaf Huang, and Chad V. Pecot
A Conditional Mouse Expressing an Activating Mutation in NRF2 Displays Hyperplasia of the Upper Gastrointestinal Tract and Decreased White Adipose Tissue
The Journal of Pathology
July 2020
Brittany M. Bowman, Stephanie A. Montgomery, Travis P. Schrank, Jeremy M. Simon, Travis S. Ptacek, Tigist Y. Tamir, Kathleen M. Muvlaney, Seth J. Weir, Tuong T. Nguyen, Ryan M. Murphy, Liza Makowski, D. Neil. Hayes, Xiaoxin L. Chen, Scott H. Randell, Bernard E. Weissman, Michael B. Major
Comprehensive nucleosome interactome screen establishes fundamental principles of nucleosome binding
Nucleic Acids Research
July 2020
Aleksandra Skrajna, Dennis Goldfarb, Katarzyna M. Kedziora, Emily M. Cousins, Gavin D. Grant, Cathy J. Spangler, Emily H. Barbour, Xiaokang Yan, Nathaniel A. Hathaway, Nicholas G. Brown, Jeanette G. Cook, Michael B. Major, and Robert K. McGinty
Gain-of-function Genetic Screen of the Kinome Reveals BRSK2 as a Inhibitor of the NRF2 Transcription Factor
Journal of Cell Science
June 2020
Tigist Y. Tamir, Brittany M. Bowman, Megan J. Agajanian, Dennis Goldfarb, Travis P. Schrank, Trent Stohrer, Andrew E. Hale, Priscila F. Siesser, Seth J. Weir, Ryan M. Murphy, Kyle M. LaPak, Bernard E. Weissman, Nathaniel J. Moorman, and Michael B. Major
In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators
PLoS Biology
December 2020
Jennifer L. Franks, Raquel C. Martinez-Chacin, Xianxi Wang, Rochelle L. Tiedemann, Thomas Bonacci, Rajarshi Choudhury, Derek L. Bolhuis, Taylor P. Enrico, Ryan D. Mouery, Jeffery S. Damrauer, Feng Yan, Joseph S. Harrison, Michael B. Major, Katherine A. Hoadley, Aussie Suzuki, Scott B. Rothbart, Nicholas G. Brown, and Michael J. Emanuele
Loss of SWI/SNF chromatin remodeling alters NRF2 signaling in non-small cell lung carcinoma
Molecular Cancer Research
August 2020
Shujie Song, Vinh Nguyen, Travis Schrank, Kathleen Mulvaney, Vonn Walter, Darmood Wei, Tess Orvis, Nisarg Desai, Jiren Zhang, D. Neil Hayes, Yanfang Zheng, Michael B. Major, and Bernard E. Weissman
PKIS deep dive yields a chemical starting point for dark kinases and a cell active BRSK2 inhibitor
Scientific Reports
September 2020
Tigist Y. Tamir, David H. Drewry, Carrow Wells, Michael B. Major, and Alison D. Axtman
PPP6C Negatively Regulates STING-Dependent Innate Immune Responses
MBio Host-Microbe Biology
August 2020
Guoxin Ni, Zhe Ma, Jason P. Wong, Zhigang Zhang, Emily Cousins, Michael B. Major, and Blossom Damania
The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis
Molecular Biology of the Cell
December 2020
Shalini Menon, Dennis Goldfarb, Tsungyo HO, Erica W. Cloer, Nicholas P. Boyer, Christopher Hardie, Andrew J. Bock, Emma C. Johnson, Joel Anil, Michael B. Major, and Stephanie L. Gupton
The Ubiquitylome of Developing Cortical Neurons
microPublication Biology
November 2020
Shalini Menon, Dennis Goldfarb, Emily M. Cousins, Michael B. Major, and Stephanie L. Gupton
Wnt Regulation: Exploring Axin-Disheveled Interactions and Defining Mechanisms by Which the SCF E3 Ubiquitin Ligase is Recruited to the Destruction Complex
Mol Bio Cell
May 2020
Kristina N. Schaefer, Mira I. Pronobis, Clara E. Williams, Shiping Zhang, Lauran Bauer, Dennis Goldfarb, Feng Yan, Michael B. Major, and Mark Peifer